Obtaining of Collagen Extracts Used as Biomaterials with Applications in the Medical Field

Abstract

Collagen is the core protein of connective tissues: skin, bone, tendon, base membrane, etc. Collagen is actually a family of several different genetic types. Currently they are known, in vertebrates, at least 27 different types of collagens, which shows a remarkable diversity in molecular and supramolecular organization of the tissue distribution and function, discovered and developed over 45 years. They were studied, in detail, 12 main types. Collagen-based bioproducts can be produced in a variety of molecular structures (micro and nano structures) in powder form, hydrogels and injectable solutions, films, membranes and matrices, etc. This paper presents the drying processes that are selected depending on the nature of the extract (undenatured or denatured) and morphological structure bioproduct or sponge, fibers or membranes. The most frequently used procedures for drying are freeze-drying and free drying at a temperature of approx. 25 ° C. Both processes produce no distorts to the extracts They are presented bioproducts derived from collagen which are used in medicine.